Additionally, although T cell is an important contributor to tumor vessel normalization7, tumor cGAS was sufficient to repress tumor angiogenesis and induce vascular normalization in immunodeficient mice (Supplementary Fig. 4a–e), excluding the essential role of T cell-intrinsic STING in tumor cGAS-mediated tumor vasculature remodeling. This evidence concerns the gene STING1 and neoplasm.