Notably, the levels of IL-6, IL-8, IL-10, IL-13, and GM-CSF were markedly upregulated in severe Dengue patients on day three after febrile symptoms compared to other groups while a decrease in MIP-1β and IL-12, suggesting that a panel of these cytokines might aid in the prediction of Dengue severity. Here, CXCL8 is linked to dengue disease.