CD274 and neoplasm: To evaluate the potential of 68Ga-FAPI PET/CT imaging in predicting tumor responses to immunotherapy in patients with metastatic CRC, we enrolled and analyzed the prognosis of 13 patients with metastatic CRC who received immunotherapy (PD-1 or PD-L1 blockade) after 68Ga-FAPI PET/CT imaging in our clinical trial at the FUSCC (Figure 3).