MGMT and neoplasm: Cox multivariate regression models (Table 4) were constructed to compare survival outcomes between the BEV Only, BEV + GK, and GK Only treatment groups while controlling for intergroup differences in age, gender, single vs. multifocal lesion, recurrence tumor volume, IDH and MGMT statuses, post-surgical KPS, number of bevacizumab cycles, steroid use, number of surgical resections, and number of other chemotherapeutic agents administered to the patients during their treatment course.