For oral cancer, IL6 (sensitivity = 84, specificity = 72, ROC Area = 0.8816, threshold = 1.074) and CXCL1 (sensitivity = 86.67, specificity = 86.96, ROC Area = 0.8812, threshold = 0.1386) expression reached the threshold sensitivity and specificity for a strong biomarker. Here, IL6 is linked to lip and oral cavity carcinoma.