The lists of these differing blood or CSF markers continue to grow, but it includes IL1B, IL2, IL6, IL8, IL10, IL12, IL17, IL18, IL1RA, CCL2/MCP1, CCL3/MIP1A, TNF, TGFB, IFNG, sTREM2, sTNF2, and CRP in both dementia and MDD; IL1A, IL3, IL11, IL22, IL23, CCL5/RANTES, CCL7/MCP3, CCL15/MIP1G, CCL18/PARC, CCL20(MIP3G), M-CSF, G-CSF, IP10/CXCL10, sTNF1, and TRAIL-R4 in dementia; and IL1RA, sIL2, IL3, IL4, IL5, IL9, IL13, IL15, and MIF in MDD [144, 148–166]. The gene discussed is TNFRSF10D; the disease is major depressive disorder.