Finally, our observations were confirmed by RT-PCR showing the amplification of cryptic exons of both STMN2 and UNC13A transcripts in the amygdala of Alzheimer’s disease patients with TDP-43 pathology, but not in the controls or Alzheimer’s disease patients without TDP-43 pathology (Fig. 2g). This evidence concerns the gene TARDBP and Alzheimer disease.