↓ Activity in neurons co-cultured with nonstimulated and IL-1β–stimulated BD astrocytes.↑ Number of IL-6–positive astrocytes after IL-1β and TNF-α stimulation.↑ IL-6 levels↑ IL-6 secretion under basal conditions and after stimulation with IL-1β. This evidence concerns the gene IL6 and Behcet disease.