LINC00623 is able to bind to N-acetyltransferase 10 (NAT10) and recruit USP39, which prevents NAT10 from ubiquitin-mediated degradation, thereby promoting tumor progression by stabilizing the downstream oncogenic mRNAs through mediating the N4-acetylcytidine modification (Feng et al., 2022). The gene discussed is NAT10; the disease is neoplasm.