Besides, in kidney cancer, bladder cancer and prostate cancer, AR has been identified to be critical to multiple tumors’ development and progression via promoting cell proliferation and suppressing apoptosis, and especially in prostate cancer, AR activity was suppressed by miR-320a (Ding et al., 2016; Pak et al., 2019; Zheng et al., 2020), which also was observed in our target network. This evidence concerns the gene AR and Familial prostate cancer.