The KM Plotter, which comprises gene expression profile information as well as the survival analysis of BC individuals, was assessed to explore the survival analysis of extremely dysregulated glucose related genes; ADH1C, ADH4, ALDH1A3, ALDOC, FBP1, PCK1, PFKFB1, PFKFB3. The gene discussed is PFKFB3; the disease is breast cancer.