PTPN3 and cancer: Combined with the significant involvement of PTPN3 in immune-related biological functions and signaling pathways by GO and KEGG analyses mentioned above, we imply that PTPN3 acts as an essential regulator of tumor immunity may influence the prognosis and therapy responses of cancer patients through mediating immune microenvironment, which requires a further understanding of the immunological activity of PTPN3.