PTPN3 and adrenal cortex carcinoma: The DSS analysis revealed that PTPN3 could act as a risk factor for patients with ACC (HR, 1.982; 95% CI 1.069–3.674; p = 0.030), PCPG(HR, 8.270; 95% CI 2.162–31.639; p = 0.002), while a protective factor for patients with KICH (HR, 0.348; 95% CI 0.141–0.860; p = 0.022), KIRC (HR, 0.429; 95% CI 0.328–0.561; p < 0.001), MESO (HR, 0.586; 95% CI 0.382–0.898; p = 0.014) and UCEC(HR, 0.601; 95% CI 0.437–0.827; p = 0.002) (Fig. 4C).