Finally, our in vivo peritoneal carcinomatosis model data showed that simultaneous systemic lactadherin blockade (using the same antibody) or lactadherin blockade in sEV-MDA231 previous to their administration had similar effects on the inhibition of mesenteric tumor micronodules and malignant ascites formation (Fig. 8). The gene discussed is MFGE8; the disease is neoplasm.