We therefore should also consider the fact that our findings for ACTL7B and KCNK3 were based upon much finer scale replication co-localisations (13 and 0 kb, respectively) between T2D studies of different ancestries based on their population-specific genetic LDU maps, which may also have contributed to their earlier discovery [5] without the use of imputation. The gene discussed is ACTL7B; the disease is type 2 diabetes mellitus.