However, since DX2 seems to act only when extra amount of AIMP2 is present, induced in a specific stress condition (Figs. 1, 2 and 3), logically its overexpression is non-oncogenic and it barely disturbs the tumour suppressive function of AIMP2 in normal condition (Fig. 6b and Additional file 1: Fig. S5) [10]. The gene discussed is AIMP2; the disease is neoplasm.