In addition, DEGs associated with the immune receptor (Lrrc19), cell chemotaxis (Ccr7, Cxcl1, Cxcl5, Cxcl9, and Cxcl10), and inflammatory response (IL1r11, IL11, Tnf, IL1β, and IL18) were also upregulated in the colonic tissue of colitis mice in DVF group (Fig. 3C). The gene discussed is IL18; the disease is colitis.