The EGR1 gene is an important transcription factor and belongs to the EGR protein family, which has been reported to be transcription factors in phosphatase and tensin homolog (PTEN) tumor suppressor genes, and Bcl-2 and Bax are important members of the Bcl-2 gene family and are closely related to apoptosis. The gene discussed is PTEN; the disease is neoplasm.