In particular, the new classification includes astrocytoma, IDH-mutant (Grade 2, 3, 4), oligodendroglioma, IDH-mutant, and 1p/19q-codeleted (Grade 2, 3) and GBM, IDH-wildtype (Grade 4) [57]. Here, IDH1 is linked to astrocytoma (excluding glioblastoma).