MUC22 and myalgic encephalomeyelitis/chronic fatigue syndrome: A pilot study examining genome wide single nucleotide polymorphisms (SNPs) in 383 ME/CFS via the commercial company 23andMe showed that approximately 70–80% of ME/CFS subjects possess abnormal variants in genes encoding for airway, eye, and salivary mucin proteins (MUC16, MUC19, and MUC22) at 1.60 to 3.75 the reference population (see Table 1) (Perez et al. 2019).