Approximately, 75 to 80 percent of ME/CFS subjects appear to have an irritant rhinitis with increased mucin production (Naranch et al. 2002; Baraniuk et al. 1998), and there appears to be a relationship between ME/CFS and dry eye syndrome (Chen et al. 2018; Qanneta et al. 2014), with a previous clinical study demonstrating that sicca symptoms existed in about 70 percent of ME/CFS patients (Qanneta et al. 2014). The gene discussed is MUC5AC; the disease is myalgic encephalomeyelitis/chronic fatigue syndrome.