A pilot study examining genome wide single nucleotide polymorphisms (SNPs) in 383 ME/CFS via the commercial company 23andMe showed that approximately 70–80% of ME/CFS subjects possess abnormal variants in genes encoding for airway, eye, and salivary mucin proteins (MUC16, MUC19, and MUC22) at 1.60 to 3.75 the reference population (see Table 1) (Perez et al. 2019). The gene discussed is MUC16; the disease is myalgic encephalomeyelitis/chronic fatigue syndrome.