In HCC, BC, ovarian cancer (OV), and HCC, lncRNAs mainly alter the expression of STAT3 by directly binding to STAT3 [52–59], inhibiting the binding of miRNAs to downstream target genes [60–67], regulating the expression of IL-6, IL-11, and IL-23 [68–80], or regulating the protein level of STAT3 [81, 82], ultimately affecting the biological phenotype of tumor cells or the occurrence and development of diseases. This evidence concerns the gene IL6 and ovarian carcinoma.