ABO and diabetic neuropathy: In addition to ABO, our analysis also yielded 210 suggestive associations at the genome-wide significance level (P < 5 × 10−8), including genetic variants associated with diabetic neuropathy (rs10773589, located close to the TMEM132D gene) that affected the presence of an Anaerostipes hadrus dSV and variants affecting expression of the FBLN5 gene (encoding fibulin 5, an extracellular matrix protein that may have a role in bacterial adhesion) that were associated with dSVs of Collinsella species.