However, further correlation analyses revealed significant correlations between the measured plasma leptin levels and percentages of classical monocytes (CM; p = 0.0117), intermediate monocytes (IM; p = 0.0143), and non-classical monocytes (NCM; p = 0.0398) in the obesity cohort but not in the OSAS cohort (Fig. 4). This evidence concerns the gene LEP and obesity due to melanocortin 4 receptor deficiency.