In several studies, in addition to alteration in leukocyte counts, high levels of pro-inflammatory molecules, such as Interleukin-6 (IL-6), Tumor Necrosis Factor-α (TNF-α), C-reactive protein (CRP), high-sensitivity CRP, and low levels of anti-inflammatory molecules namely Transforming Growth Factor-β (TGF-β) and Interleukin-10 (IL-10) have been found in both serum and follicular fluid of women with PCOS as compared with healthy controls [23, 24]. Here, TNF is linked to polycystic ovary syndrome.