In the Chinese population, it has been demonstrated that NSHL is closely associated with genetic polymorphisms of gap junction protein β2 (GJB2), gap junction protein β3 (GJB3), solute carrier family 26 member 4 (SLC26A4), and mitochondrial DNA (mtDNA) 12S ribosomal RNA (12S rRNA)7. This evidence concerns the gene SLC26A4 and nodular sclerosis classical Hodgkin lymphoma.