Patients with Ph+ B-ALL with IL-17A mRNA expression (208402_at) above the median level (IL-17A high) exhibited positive NES but no enrichment of the inflammatory response, IL6/JAK/STAT3 signaling and hallmark TNF signaling via NF-kB pathways compared with patients with leukemia with IL-17A mRNA expression below the median level (IL-17A low) (Supplementary Fig. 4c, d). This evidence concerns the gene STAT3 and acute lymphoblastic leukemia.