For instance, circEHBP1 served as a miRNA sponge for miR-130a-3p to regulate the TGFβR1/VEGFD axis, leading to increased levels of VEGFD and lymph vessel density in the context of bladder cancer.203 Additionally, some circRNAs are transported from cancer cells to LECs via exosomes. The gene discussed is VEGFD; the disease is urinary bladder cancer.