In the context of glioblastoma, VEGFC-induced meningeal lymphangiogenesis recruited CD8+ T cells into the tumor and induced a long-lasting antitumor memory response.126 In response to spinal cord injury, VEGFC/VEGFR3 signaling activation-mediated spinal lymphangiogenesis enhanced the immune response by increasing the T cell infiltration rate.127 However, studies have shown that meningeal lymphatic vessels potentially promote pathological processes under autoimmune neuroinflammatory conditions. Here, FLT4 is linked to neoplasm.