We noted that, in four gene pairs (EIF3A-AK2, EIF3A-EMP3, YTHDC1-IGFBP2, YTHDC1-TUBA1C), the expression level of the m6A regulator is significantly higher than its target gene in the LGG patients, whereas the expression of IGF2BP3 is up-regulated in GBM patients. The gene discussed is TUBA1C; the disease is glioblastoma.