The introduction of the new nomenclature for clinical disease related to TDP‐43 pathology – limbic‐predominant age‐related TDP‐43 encephalopathy, or LATE,67 and LATE neuropathologic changes, or LATE‐NC – followed more than a decade of published papers in AD/ADRD research addressing the relationship of TDP‐43 with our without AD pathology and memory loss (without clinical diagnosis of FTD) or TDP pathology specifically with AD neuropathologic changes.68, 69, 70, 71. The gene discussed is TARDBP; the disease is frontotemporal dementia.