MAPT and Alzheimer disease: Human brain tissue from patients with AD26, 30, 32 and frontotemporal dementia (FTD) due to the MAPT IVS10+16 mutation31 features invaginations of the nuclear envelope that harbor disease‐associated phosphotau, in line with electron microscopy‐based analyses in 2006 that reported “nuclear contour irregularity” in AD.33