SOD1 and amyotrophic lateral sclerosis: The team investigated post mortem motor cortex samples from 47 people with ALS and 25 controls (including five with a C9ORF72 expansion and one with an SOD1 mutation) and were able to report for the first time that pTau‐S396 is mislocalized to synapses in post mortem motor cortex across ALS subtypes.