An optimized formulation of sodium valproate-loaded nanospanlastics has recently been assessed and proven effective in the treatment of androgenetic alopecia (AGA) [5], which is postulated to act through upregulation of the Wnt/beta-catenin signaling pathway via inhibition of GSK-3b, in simulation to its effect on the neuronal cells [19]. The gene discussed is GSK3B; the disease is androgenetic alopecia.