GPT and metabolic dysfunction-associated steatotic liver disease: Curcumin supplemented at a dose of 500 mg to 1,000 mg for 8–12 weeks was reported to reduce AST (−2.7 to −9.2 IU/L) and ALT (−2.9 to 2212-11.3 IU/L) in NAFLD patients in earlier studies (12, 42–44).