The results showed that the level of expression of GSDMB and GSDMD mRNA was not significantly related to the chemotherapeutic PFS of SCLC patients (Supplementary Figures 1A-B), but SCLC patients with high expression of GSDME had higher PFS (P = 0.0225, Figure 1A) and OS (P = 0.0249, Figure 1B). The gene discussed is GSDME; the disease is small cell lung carcinoma.