Previous studies reported that FOXC1 increased glucose uptake and improved insulin sensitivity and had a role in the pathogenesis of GDM by attenuating the high-glucose (HG)-induced trophoblast damage by upregulating the FGF19-activated AMPK signaling pathway (46).Our search for miRNAs that bind to CD3G and YES1 led to the identification of hsa-mir-4459. Here, FGF19 is linked to gestational diabetes.