In melanoma, lncRNA MSC-AS1 promotes the pathological process by binding to miR-302a-3p 30, lncRNA MIAT can promote proliferation, migration, and invasion in melanoma through recruiting TCF12 31, and lncRNA HCG18 facilitates melanoma progression by modulating the miR-324-5p/CDK16 axis 32. The gene discussed is HCG18; the disease is melanoma.