In contrast, the mRNA expression of ARL-6 was markedly lower in UCEC (uterine corpus endometrial carcinoma), THCA (thyroid carcinoma), SKCM (Skin Cutaneous Melanoma), READ (Rectum adenocarcinoma), PRAD (prostate adenocarcinoma), LUSC (lung squamous cell carcinoma), LUAD (lung adenocarcinoma), KIRP (kidney renal papillary carcinoma), KIRC (kidney renal clear cell carcinoma), BRCA (breast invasive carcinoma), and BLCA (bladder urothelial carcinoma) (Figure 1A). This evidence concerns the gene ARL6 and rectum adenocarcinoma.