NFKB1 and cancer: Notably, this tumor-suppressive effect can be stimulated by diallyl trisulfide (DATS), a compound derived from garlic known to thwart the progression of GC.439 In keeping with the ability of zinc to inhibit NF-kB activation in cancer cells,440–442 zinc chelation likely plays a part in the anti-GC activity of the MT2A/MZF1–NF-kB pathway mediated by DATS.