Additionally, left ventricular noncompaction (LVNC) is a cardiomyopathy caused by arrested compaction, characterized by excessive trabeculation with deep intertrabecular recesses and thin compact myocardium.503 ZIP8 has been identified as a crucial factor in ventricular trabeculation and compaction, revealing a potentially novel regulator of ventricular myocardial development. Here, SLC39A8 is linked to left ventricular noncompaction.