Recently, LINC00659 expression has also been found to be increased in inferior vena cava tissues and peripheral blood of lower extremity DVT, and overexpression of LINC00659 inhibits EPC migration, proliferation, and angiogenesis by activating DNMT3A-mediated FGF1 promoter methylation [72]. The gene discussed is LINC00659; the disease is deep vein thrombosis.