Recently, we have demonstrated that RNA-edited AZIN1 promotes tumor angiogenesis through delaying c-Myc degradation by OAZ2-mediated ubiquitin independent proteasome pathway to increase IL-8 [89], which suggests an important contribution of RNA-edited AZIN1 to the tumor vascular microenvironment and highlights its translational potential. The gene discussed is AZIN1; the disease is neoplasm.