PIGT and urinary bladder cancer: Chen et al. have demonstrated that regulation of m6A RNA methylation affects malignant progression of bladder cancer, and suggested that m6A RNA methylation regulators may be promising prognostic biomarkers [16]. m6A RNA methylation also enhances bladder cancer progression [17]. However, the roles of PIGT and m6A RNA methylation in bladder cancer are poorly understood and remain to be elucidated.