FN1 and posterior cortical atrophy: Fibronectin is not only a ligand for αV‐class integrins, but it also sequestrates latent TGFβ complex and is essential for TGFβ activation.[34] Whether an integrin switch from laminin‐(α6β4) and collagen‐binding (α1β1 and α2β1) integrins to RGD‐binding integrins (αV‐class integrins and α5β1) is indeed driving PCa tumorigenesis merits further studies.