PRL and amenorrhea: Musa ibn Maimon (Maimonides) mentioned that amenorrhea can result in serious consequences such as feeling pins and needles in the limbs, backache, visual disturbances, or swelling of the breasts and appearance of milk secretion (which is now recognized as galactorrhea, and it is present in amenorrhea associated with high serum prolactin levels typically due to pituitary gland adenoma) [17].