In the current study, we found that scutellarin inhibited cell migration and also elevated E-cadherin expression and reduced N-cadherin and α-SMA expression in experimental asthma models, indicating that scutellarin can inhibit the EMT process by recovering E-cadherin expression and suppressing N-cadherin and α-SMA induction following asthma. Here, CDH1 is linked to asthma.