We created a signature of 13 DSP-associated genes (POU4F1, KIF7, DPP7, NECAB2, MAP2, ASB6, TFAP2C, ZNF160, JDP2, FAM219B, GDI1, GPC1, and SLC35G2) and found that it can predict OS in patients with CRC. The gene discussed is NECAB2; the disease is colorectal carcinoma.