The results showed that BMDCs pre-cultured with Ogt+/+ or Ogt−/− B16-OVA tumor cells supernatant provided a potent activated signal for optimal single epitope-specific T cell proliferation (Fig. 3M), while cGAS or STING deficiency in Ogt−/− tumor cells diminished such effects (Fig. 3N). This evidence concerns the gene OGT and neoplasm.