Out of the enriched pathways from DMR-associated genes following TET1 knockdown, 59.6% were also enriched in DMR-associated genes following HDM treatment, including Pulmonary Fibrosis Idiopathic Signaling Pathway, Nitric Oxide Signaling in the Cardiovascular System, Leukocyte Extravasation Signaling, and IL-8 Signaling. The gene discussed is CXCL8; the disease is pulmonary fibrosis.