CD8A and cancer: FACS-based analyses using the fluorescent fatty acid analog C1-BODIPY 500/510 C12 showed that CD8+ T cells residing in the ascites of patients with high-grade serous OvCa (HGSOC), the most common and aggressive form of OvCa20, demonstrate defective lipid uptake compared with peripheral CD8+ T cells isolated from cancer-free women (Fig. 1a).