Additionally, the mRNA level of CD36 (fatty acid transporter, a marker of fatty liver disease) of Mic19 LKO mouse liver (3 months old) was more than 10 times that of control mouse liver under fed or fasted conditions (Fig. S6a), indicating that lipid uptake may contribute to Mic19 LKO-induced lipid accumulation in mouse liver. Here, CHCHD3 is linked to fatty liver disease.