CD8A and neoplasm: Importantly, despite normal influx of OT-1 T cells and other immune subsets (Supplementary Fig. 6c, d), combination treatment in CXCR3 KO mice failed to induce durable responses, thereby implying that the influx of endogenous CD8 T cells was essential for the anti-tumor response (Fig. 4f and Supplementary Fig. 6e).