This increase in p-tau uptake contrasts with the previous study demonstrating reduced microglial Aβ uptake in the AD retina [13], but while the latter is suggested to be due to a reduced capacity to remove Aβ (and thereby contributing to the accumulation and deposition of Aβ in brain and retina), microglial p-tau engulfment may contribute to AD pathology in a different manner. Here, MAPT is linked to Alzheimer disease.