However, quantitative analysis did not reveal any significant difference between control subjects and PD patients in either the percentage of astrocytes positive for acetylated α-Tubulin (Supplementary Fig. 1c) or the co-localization between S100β and acetylated α-Tubulin (Mander’s coefficient; Supplementary Fig. 1d). The gene discussed is S100B; the disease is Parkinson disease.