NAT10 and systemic lupus erythematosus: Moreover, ROC curve was drawn to assess the potential predictive value of the mRNA expression level of NAT10 in PBMC for new-onset AS, and the results showed that the AUC for distinguishing new-onset AS from RA and SLE patients was up to 0.723 (95% CI = 0.620–0.826, P = 0.0003; Fig. 7B), with a cutoff value of < 0.8078, a sensitivity of 67.86%, and a specificity of 75.00%.